ADVANTAGES
- Neat and elegant in appearance.
- Enclosing the medication within capsule shells
provides a tasteless, odourless means of administering medication.
- The ready solubility of gelatin at gastric pH
provides rapid release of medication in the stomach.
- Since hard
gelatin capsules may be compounded by the pharmacist, this dosage form
offers physician’s greater
- Flexibility in dosages and drug combinations than
is available with prefabricated medication.
DISADVANTAGES
- Capsules are not suitable containers for liquids
that dissolve gelatin, such as aqueous or hydroalcoholic solutions.
- Very soluble salts, such as bromides or iodides
should not be dispensed in capsules, as the rapid release of such
materials
- may cause gastric irritation.
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